Preparation of adenocarcinoma from intestinal (Wiki)

People who suffer from a form difficult to combat colon cancer, may benefit from a combination of existing drugs. 

Mutation

The patients suffering from colon cancer with a mutation in the BRAF gene. At this moment there is no effective cure for this type of cancer. Exactly the same mutation also occurs in patients with melanoma . This medication has been successful, but this does not work in cancer patients. Lang was unclear why.Researchers at the NKI-AVL seen what happens if gene by gene is turned off. In this way was the cause of the resistance found quickly.

Dual control

When the BRAF protein in colon cancer is inhibited, leads to activation of EGFR, another protein that stimulates cell division. But if both proteins are inhibited by drugs, the cancer cells die.